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Titration Plan (Once Daily) Gradual titration on a 20 mg blend reconstituted with 3.0 mL BAC water Week Weeks 1-2 Dose (each peptide) 100 mcg Insulin units 3 units Volume 0.03 mL Week Weeks 3-4 Dose (each peptide) 150 mcg Insulin units 4.5 units Volume 0.045 mL Week Weeks 5-8 Dose (each peptide) 200 mcg Insulin units 6 units Volume 0.06 mL Week Weeks 9-12 Dose (each peptide) 200-300 mcg Insulin units 6-9 units Volume 0.06-0.09 mL These are research-planning ranges drawn from common protocol summaries (Teichman 2006 dosing studied CJC-1295 with DAC, not no-DAC)

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GH stimulation testing and random GH measurements have limited diagnostic utility for monitoring IGF-1 analogue use because exogenous LR3 suppresses pituitary GH output, creating a dissociation between GH and IGF-1 levels that may mislead interpretation [18]

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