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Given the lack of evidence supporting a potential effect of GLP-1 receptor agonists as treatment in methamphetamine (METH) dependence in either a clinical or preclinical setting, the aim of this study was to investigate whether administration of liraglutide could reduce METH intake in a rat model of intravenous self-administration (IVSA)

Thus, careful monitoring during the first weeks of GLP-1 therapy is critical

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Insulin sensitizers: thiazolidinediones These drugs improve insulin sensitivity in target organs, while the peroxisome proliferator-activated gamma receptor (PPAR) has selective agonist effects