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All enrolled patients provided a medical history that included information on smoking and potential exposure to inhaled antigens and underwent a medical examination that involved: a chest X-ray, HRCT of the chest, pulmonary function tests, and bronchoscopy with bronchoalveolar lavage (BAL)

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A copper-binding tripeptide commonly referenced in scientific literature for its role in cellular communication , copper transport , and gene expression modulation

This sensitivity to DNA-damaging agents was not rescued by KG, l-carnitine or acetylcarnitine (Extended Data Fig