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The metabolic programs implicated here, spanning redox metabolism, immunemetabolic signaling, and alternative substrate utilization, are increasingly recognized as central to neural resilience and neurological disease, suggesting that the biology identified in this setting may have broader relevance beyond NPH 7984

We have an obligation to understand the full biology of these drugs, not just the intended effect

Results from prospective studies have also suggested that increased folate intake may reduce the risk of breast cancer in women who regularly consume alcohol (145, 147-150)

"Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase"