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Our innovation here was to use the upper end of CrATs substrate range, C 8 -carnitine, for which the endogenous pool is very small and for which a minimally regulated metabolic sink (medium-chain mitochondrial FAO) is in place to rapidly catabolize the acyl-CoA product and keep the CrAT reaction moving in the desired reverse direction

J Exp Bot 60:29332943

Overexpressing the mutated fas1 R1834K increased the production of medium-chain fatty acids (C8C12) and resulted in an MLM content of 0.41 mol% of the total TAGs

The Regulatory Picture Not all peptides have the same legal status, and that matters when youre deciding what to put in your body