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People with existing kidney conditions If you have chronic kidney disease (CKD), any change in urination warrants closer monitoring

Outcomes The primary outcome in our network meta-analysis was MACE, defined as the composite of cardiovascular mortality, nonfatal myocardial infarction (MI), and nonfatal stroke

Histological analyses of brain and adipose tissues To assess changes in adipose tissue, the epididymal fat contents of the animals were harvested immediately following the termination of the experiments

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