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The progressive disorder can come both before and after heart failure, or it can follow a variety of conditions, including congenital heart disease, autoimmune conditions like connective tissue disease, coronary artery disease, high blood pressure, liver disease (cirrhosis), blood clots to the lungs, or chronic lung diseases like emphysema

Actually, even when isolated mitochondria are motivated by the ADP for full respiration at saturating oxygen tension, only part of the total COX capacity is utilized (154)

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