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PubMed , Molecular Biotechnology , vol

Surprisingly, SGLT2i are lipid-soluble drugs with the ability to cross the blood-brain barrier (BBB) (Pawlos et al

Modern incretin-based pharmacotherapy can approach surgery-like short-term weight reduction in some patients, but metabolic/bariatric surgery remains among the most durable interventions for severe obesity and obesity-related complications

The definition of moderate certainly is that we are moderately confident in the effect estimate (the true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different)