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According to clinical trial data from the STEP trials, 43.9% of patients taking semaglutide 2.4 mg experienced nausea at some point during treatment, with the majority of episodes occurring during or immediately after dose increases

Oral semaglutide vs sitagliptin: efficacy by baseline HbA1c and background OAD in PIONEER 3

So if you know you want to start trying for a baby in June, for instance, your doctor will likely recommend halting your semaglutide doses by the end of March and continuing with your contraceptive use through April and May

For eligible patients, semaglutide can be an effective adjunct to a healthy lifestyle, supporting both metabolic health and weight reduction when combined with diet and exercise