The combination of a BET inhibitor (+)-JQ-1 and a proteasome inhibitor bortezomib (BTZ) has been shown to decrease GPX4 expression, thereby inducing ferroptosis in TNBC [18]
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Prez GV, Rosales M, Ramn AC, Rodrguez-Ulloa A, Besada V, Gonzlez LJ, Aguilar D, Vzquez-Blomquist D, Falcn V et al (2023) CIGB-300 anticancer peptide differentially interacts with CK2 subunits and regulates specific signaling mediators in a highly sensitive large cell lung carcinoma cell model
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