Ultimately, it depends on what youre trying to treat, how your body responds, your metabolic state, and what your doctor thinks is best for you
We're in the wild west of this right now
Cotadutide (MEDI0382) is the most extensively developed dual GLP-1/glucagon receptor agonist, showing significant improvements in glucose control, BW (likely mediated by reduced energy intake rather than increased energy expenditure), hepatic fat, and albuminuria in a small RCT on patients with T2D and overweight or obesity 45,46
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