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They are often due to: Immune response to the peptide itself Histamine release at the injection site Irritation from benzyl alcohol, preservatives, or buffers Needle trauma or poor injection technique Using the same site repeatedly without rotation Suboptimal reconstitution (too concentrated or acidic solution) Contaminants in low-quality peptides from unregulated sources The body may react to peptidesespecially new onesas foreign substances, causing a mild inflammatory or immune response

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PF and PRP groups showed significantly higher implant stability values than the control group from 2 to 12 months, suggesting that photofunctionalization may not only accelerate osseointegration but also enhance the attained level of final-stage osseointegration over time