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Since AgRP neurons are critically involved in neuroendocrine adaptations induced by weight loss 12, 16, 17 , control and AgRP GHR KO mice were further studied either in ad libitum or during 60% food restriction (F.R.)

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CJC-1295 + Ipamorelin is a research peptide blend combining a DAC-modified GHRH analogue (CJC-1295) with a selective ghrelin-receptor agonist (Ipamorelin)