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It upregulates genes involved in collagen synthesis (COL1A1, COL3A1, COL5A1), extracellular matrix remodeling (decorin, fibromodulin), and antioxidant defense (superoxide dismutase, glutathione peroxidase) while simultaneously suppressing genes associated with inflammation (IL-6, TNF-alpha), fibrinogen production, and tissue destruction (several MMPs)

To view a copy of this licence, visit About this article Cite this article Chen, H., Liu, S., Gao, S

A doping/sport note (because it comes up in searches) WADAs prohibited list explicitly references growth hormone fragments, including AOD-9604 / hGH 176191

Beneficial effects of crocin against depression via pituitary adenylate cyclase-activating polypeptide