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In clinical trials, many people reached about 5% weight loss around 12 to 16 weeks of treatment , often just as they were approaching higher doses

Liraglutide, a oncedaily human GLP1 analogue, added to a sulphonylurea over 26 weeks produces greater improvements in glycaemic and weight control compared with adding rosiglitazone or placebo in subjects with Type 2 diabetes (LEAD1 SU)

Metformin also works well as a foundation medication when combined with GLP-1 therapy

Ferulic acid provides neuroprotection against oxidative stress-related apoptosis after cerebral ischemia/reperfusion injury by inhibiting ICAM-1 mRNA expression in rats