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La dosis inicial estndar para adultos es de 2.5 mg, que puede aumentarse a 5 mg, 7.5 mg o 10 mg segn la respuesta y la tolerabilidad individual

To overcome challenges such as biosafety, off-target effects, and clinical translatability, strategies successfully explored in other diseases, such as biodegradable or organicinorganic hybrid nanozymes, pH-responsive targeting designs, erythrocyte membrane coatings, and ROS-responsive carriers, may be adapted to enhance tissue specificity and safety in IMID treatment

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