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In addition, they reviewed the gutTMAOHF axis as a new target for HF treatment (Zhang et al., 2021b)

They should be approached with realistic expectations and appropriate screening

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In contrast, HepG2 ATP7B-KO cells exhibited significant, dose-dependent upregulation of all six genes after 6 h, with sustained expression of GABARALP1 , PRAGC , and LAMTOR3 at 24 h