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10.2337/db07-0563 108

In streptozotocin-induced diabetic mice, liraglutide treatment for 28 days was found to inhibit high glucose and interleukin (IL)-1-induced EndMT in endothelial cells and consequently attenuate neointima formation via activation of the AMPK pathway, which was evidenced by a reduction of the expression of mesenchymal markers such as smooth muscle 22 (SM22), vimentin, and Snail [51]

Advantages Fastest and most consistent insulin absorption Large surface area, making rotation easier Easy to access for self-injection Generally less painful than other sites The abdomen has a good blood supply, which helps insulin enter the bloodstream more efficiently

Description For use in Vitamin B-12 deficiency associated with cobalt deficiency in cattle and sheep and for Vitamin B-12 deficiency associated with inadequate Vitamin B-12 intake or intestinal malabsorption in swine and horses