switching from semaglutide to mounjaro Ozempic Mounjaro: How to Switch Safely How to Switch from Wegovy

Another point to keep in mind is that most patients will not have any weight loss during the first 4-5 weeks as you become accustomed to the medication, prior to increasing your dose

References Deanfield, John et al., Semaglutide and cardiovascular outcomes by baseline and changes in adiposity measurements: a prespecified analysis of the SELECT trial, The Lancet, Published on October 22, 2025, DOI: 10.1016/S0140-6736(25)01375-3 Semaglutide Effects on Heart Disease and Stroke in Patients With Overweight or Obesity (SELECT), ClinicalTrials.gov ID NCT03574597,

They are not a plan

Ensure that your treatment trial is long enough to account for these types of normal variation