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The production process is regulated by enzymes such as tyrosinase, which plays a central role in converting the amino acid tyrosine into melanin

It is synthesised within cells in two sequential ATP-dependent steps, and maintained in its biologically active reduced form (GSH) through the activity of glutathione reductase using NADPH

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Br J Ind Med 48:243246 Shang N, Zhang L, Wang S et al (2021) Increased aluminum and lithium and decreased zinc levels in plasma is related to cognitive impairment in workers at an aluminum factory in China: a cross-sectional study