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Therefore, ATF4 may play an important role in maintaining cell viability and preventing lipid oxidation 116

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Vitamin B12 deficiency: Symptoms, causes & treatment

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277 Abnormal NAD + metabolism in the pathophysiological condition Given the essential regulatory role of NAD + in fundamental physiologies, NAD + metabolic abnormalities contribute to the pathophysiology of various diseases, such as infection, cancers, metabolic diseases, aging and age-associated neurodegeneration disorders

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