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In addition, Ab#2_GLP1 retained similar human GLP-1R potency and maximum efficacy relative to the control GLP-1 analogue peptide Fc fusion molecule GLP-1-Fc(4) (Fig

GLP-1 activates specific neurons in the hypothalamus that signal satiety (fullness) whilst inhibiting neurons that drive hunger

However, research on microbiota transplantation remains limited, and uncertainties persist regarding its effects on microbiota from different ecological niches, the optimal transplantation dose, long-term clinical effects, and safety