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13% decrease in subcutaneous fat mass 30% reduction of intra-abdominal fat mass 3-11% lean body mass increase 11-19% improvement in aerobic function Muscle strength increases between 7-19% After one year, participants saw overall body fat reduction, with the most significant results in the abdomen, with belly fat reduction at a notable 61%

These insights have driven the development of synthetic GLP-1R/GCGR co-agonists aimed at achieving long-term metabolic benefits

Bottom line: For now, people with a personal or family history of medullary thyroid cancer should avoid Ozempic and other GLP-1s