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Disruption of the murine Glp2r impairs Paneth cell function and increases susceptibility to small bowel enteritis

4 Inflammasome-mediated liver injury: DAMPs released from stressed hepatocytes, damaged mitochondria, and necrotic liver cells activate inflammasome sensors, triggering the oligomerization and activation of inflammasome components

Indeed, circulating autoantibodies may detect modified forms of these antigens, potentially enhancing identification of those subjects who test negative to assay for the unmodified autoantigen (86, 134, 135)

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