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Through AKT, the binding of insulin to its receptor starts a cascade of kinase activity (Ahmed et al., 2014)

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5a), a pro-drug that combines sulphapyridine (an antibiotic) and 5-aminosalicylic (an anti-inflammatory agent) linked by an azo bridge, has huge therapeutic potential, but is, unfortunately, labile under physiological conditions (70% degradation by colonic bacteria via azo cleavage

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So, doctors keep a close eye on how patients do and adjust treatments as needed

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