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Activation of the GLP-1 receptor-mediated cAMP/PKA pathway is also involved in the protection of astrocytes from AGE-induced inflammatory response and from inflammatory cytokine secretion [83, 84]

Un riesgo bajo pero clnicamente relevante Los estudios epidemiolgicos a gran escala citados por la EMA sealan que los pacientes adultos con diabetes tipo 2 tratados con semaglutida tienen aproximadamente el doble de riesgo de desarrollar NAION en comparacin con aquellos que no reciben este frmaco