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If your BMI is over 35 with significant health conditions like Type 2 diabetes or sleep apnea, or if youve already tried GLP-1 medications without reaching your target weight, bariatric surgery may offer more permanent results

In contrast, systems such as microfluidic-assembled nanocapsules or electrosprayed powders remain below TRL 5 due to cost, complexity, or scalability constraints (194, 195)

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