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Study 4 was a 68-week trial that enrolled 611 patients with obesity (BMI greater than or equal to 30 kg/m2) or with overweight (BMI 27 to 29.9 kg/m2) and at least one weight-related comorbid condition such as treated or untreated dyslipidemia or hypertension

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Concomitant antidiabetic therapies were frequently reported, with metformin being the most frequently reported concomitant medication (n = 1,879), followed by pioglitazone (n = 478), insulin glargine (n = 474), glipizide (n = 467), and glimepiride (n = 345) (Figure S1)