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A: Short-term weight loss may temporarily improve climbing or running economy, but rapid loss of lean mass, chronic under-fuelling and impaired recovery can ultimately reduce long-term performance

Washington University and SK Biosciences took a similar approach, genetically fusing SARS-CoV-2 RBD on the exterior surface of the two-component protein nanoparticle I53-50, which is a computationally designed 120-subunit complex with icosahedral symmetry constructed from trimeric (I53-50A) and pentameric (I53-50B) components

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Single-nuclei transcriptomes from sALS and C9orf72 ALS revealed that C9orf72 hexanucleotide repeat expansion impairs the microglial cell state transition to activated state compared to sALS (Masrori et al., 2025)