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Achieving a healthy weight with ketogenic therapy is not considered remission of obesity, because its assumed that either the ketogenic therapy will stop working or the patient (or physician) will not maintain the diet

[1] Primarily, it stimulates insulin secretion from the pancreas when blood glucose levels are elevated, whilst simultaneously suppressing the release of glucagon, a hormone that raises blood sugar

Patients should never adjust their prescribed dose without consulting their healthcare provider, as semaglutide requires gradual dose escalation to minimize gastrointestinal adverse effects

Vomiting, diarrhea, constipation, and reflux symptoms are also reported