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Declining B12 despite supplementation may indicate an absorption issue requiring higher-dose supplementation

The mitochondrial fusion/fission-associated proteins Mfn2 and Drp1 have been proposed to function as downstream nuclear transcription factors in the PGC-1-mediated mitochondrial biogenesis process (Peng et al., 2017)

Targeting JAK-STAT signaling to control cytokine release syndrome in COVID-19