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Interregional variation of longitudinal relaxation rates in human brain at 3.0 T: relation to estimated iron and water contents

doi: 10.1056/nejmra1715715 5 YeteSDSouzaWSaranathD

These effects are likely partly due to local increases in extracellular glutamate causing excitotoxicity, and reduced trophic support [e.g., platelet-derived growth factor (PDGF)] from astrocytes (Tognatta et al., 2020)