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They [the findings] suggest that this drug class, typically used for managing diabetes and obesity, may serve as a dual-purpose treatment for patients with RA, addressing both systemic inflammation and associated comorbidities, such as cardiovascular disease, which is especially prevalent in patients with RAO and remains the leading cause of death in patients with RA overall, they said

The removal rate of acylcarnitine clearly decreases as the carbon chain length increases because it increases their molecular weight and alters their lipophilicity

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After excluding variants with a call rate below 95% ( n = 1,931), discordant variants in duplicate samples ( n = 493) and monomorphic variants ( n = 77,179), 646,504 variants and 2,291 samples passed quality control screening