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Click to read the study, published today in NEJM Relevant Reading: The Interleukin-17 Pathway in Psoriasis and Psoriatic Arthritis: Disease Pathogenesis and Possibilities of Treatment In-Depth [randomized controlled trial]: This study enrolled a total of 168 patients randomized 1:1:1 into the following groups: brodalumab 140mg, brodalumab 280mg and placebo

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This disruption of DNA replication and repair and HSP protein refolding can trigger mitotic arrest and even apoptosis when injury is severe

This conceptual framework led to the hypothesis, now influential in clinical practice, that restoring a physiologic MI: DCI balance may outperform DCI monotherapy for reproductive endpoints (161)