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studies may be attributed to several factors

When a DPP-4 inhibitor is added to a sulfonylurea regimen, the sulfonylurea dose may need to be reduced Pioglitazone offers similar glycaemic efficacy to gliptins but is associated with fluid retention and fracture risk DPP-4 inhibitors are generally considered weight-neutral , which is an advantage over sulfonylureas and insulin

*Correspondence: Shokrollah Elahi, [email protected] ORCID: Shokrollah Elahi, orcid.org/0000-0002-7215-2009 Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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