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The discovery work measured both arms directly, higher carnitine shuttles and -oxidation intermediates alongside faster glucose clearance, so MOTS-c is not a switch from glucose to fat

Dead-end complex, lipid interactions and catalytic mechanism of microsomal glutathione transferase 1, an electron crystallography and mutagenesis investigation

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Passeri M, Iannuccelli M, Ciotti G, Bonati PA, Nolfe G, Cucinotta D., "Mental impairment in aging: selection of patients, methods of evaluation and therapeutic possibilities of acetyl-L-carnitine", International Journal of Pharmacology Research, 1988(vedi fonte) 5