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While the weight-loss effect of GLP-1 analogs is largely attributed to potent suppression of food intake, this reduction in food intake affects not only fat mass but also muscle mass [39]

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Similar copper-peptide frameworks have been studied for their stability and compatibility with living systems [3]

A double-blind randomized controlled trial that divided healthy subjects into four groups with or without wheat bran (WB) and barley (BM) for a 4-week intervention found that the WB intake group had significantly higher fecal butyrate concentrations and a greater abundance of butyrate-producing bacteria (such as Ruminococcus , Faecalibacterium , and Roseburia ) compared to the non-WB group