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The review's recommendation, embedded in the discussion section, is that delivery enhancement through microneedling or fractional radiofrequency materially expands what topical EGF can do [17]

At the same time, this type of intervention is suboptimal due to the high risk of suture suppuration and the need to perform a full-fledged abdominal surgery using general anesthesia

It is most popularly known for its use in the cosmetic industry, where it is used to improve the health of skin and reduce signs of ageing, although its application extends beyond this, and it is currently also being investigated for additional medical uses

CAS 307297-39-8) is a synthetic tetrapeptide with the four-amino-acid sequence Ala-Glu-Asp-Gly (AEDG)