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5 The primary players found in the endometriotic milieu are interleukin-2 (IL-2), interleukin-8 (IL-8), interleukin 10 (IL-10), interleukin-27 (IL-27), interleukin-1 (IL-1), interferon (IFN-), tumor necrosis factor (TNF-), cyclooxygenase-1 (COX-1), cyclooxygenase-2 (COX-2), and prostaglandin E2 (PGE2)

Side Effects and Safety Concerns Common Side Effects Nausea Vomiting Fatigue Diarrhea or constipation Acid reflux These typically fade within the first 46 weeks as your body adjusts