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6.1 Abnormal uterine bleeding AUB refers to any irregular uterine bleeding, including changes in rhythm, frequency, duration, or volume, persisting for six months or longer in non-pregnant women ( 6.2 Endometrial polyps EP represent benign lesions characterized by focal overgrowth of the endometrium, closely associated with obesity-related microenvironmental alterations

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Similarly, the expression of key autophagy genes, such as ATG5 , ATG7 , and BECN1 , is downregulated during normal aging in the human brain [209]

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