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This suggested that the CD36/MAPK/JNK pathway may play a key role in TMAO-induced foam cell formation ( in vitro study found that different concentrations of TMAO have no effect on the formation of foam cells in mouse macrophages ( The NLRP3 inflammasome is a polyprotein complex formed by the activation of PRRs that was recently reported to be crucial for the development of AS (Martinon et al., 2002

Impaired Wnt signaling in the prefrontal cortex of Alzheimers disease

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In the past 15 years, GLP-1RAs have emerged as efficacious therapies in T2D and obesity, with evidence also indicating potential in CV disease and NASH