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24th meeting of the Federation of the European Biochemical Society Febs

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PMCID: PMC111149 Xie Y et al (2012) H2 enhances Arabidopsis Salt Tolerance by manipulating ZAT10/12-Mediated antioxidant Defence and Controlling Sodium Exclusion

Before the promising therapeutic impact of miRNA can be realized, there are several challenges to be addressed, which include but not limited to targeted delivery of oligonucleotides to specific organs, tissues and cell types, poor bioavailability, limited tissue permeability (Stylianopoulos and Jain, 2013), potential drug resistance, and instability (Raemdonck et al., 2008)