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Hero C, Rawshani A, Svensson A-M et al (2016) Association between use of lipid-lowering therapy and cardiovascular diseases and death in individuals with type 1 diabetes

And thats the kind of danger zone that the female athlete triad is all about: when chronic energy deficiency becomes too much and suppresses reproductive function and suppresses the formation of bone. That leads to low estrogen levels too

[11] It's important to note that individual results vary considerably, and not all patients experience proportional abdominal fat reduction relative to overall weight loss

If you were to use the entire contents of the vial in a single application, immediately after reconstitution, this would be an acceptable choice