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GIP/GLP-1 co-agonists, developed by merging the respective peptide sequences, potently lower body weight in rodents and humans 27,28
Metformin contains no GLP-1 activity whatsoever, making it fundamentally different from modern peptide-based therapies that directly target appetite centers in the hypothalamus
Compounded medications may not be suitable if you have difficulty with manual dexterity or vision problems that make measuring precise doses challenging
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