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In ATTAIN trials, gastrointestinal effects were the most common cause of discontinuation
Methods We assessed ileoileal anastomosis dehiscence macroscopically, histologically, and biomechanically (volume [ml] infused through a syringe-perfusion pump system (1 ml/10 s), and pressure [mmHg] to leak induction [catheter connected to a chamber and a monitor, at 10 cm proximal to anastomosis]), at 1, 2, 3, 4, 5, 6, 7, and 14 days
Fatigue setting in: Once the muscles become acidic, the conditions prevent the breaking down of glucose, reducing the muscle's ability to contract to cause fatigue
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