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However, obese people often show elevated tongue fat which, might be a local source of adipokines affecting taste signaling [132]

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Thus, oral semaglutide can be reasonably considered as another drug in the GLP-1RA class for treating T2D patients

It is certainly possible that individuals with overweight or obesity who take semaglutide may experience depressive symptoms or suicidal ideation or behavior, but the data suggest that persons not taking semaglutidein the placebo group in this studyare equally likely to experience these conditions, said Gregory Brown, PhD, a study co-author and Director of the Penn Center for the Prevention of Suicide at the Perelman School of Medicine