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discontinue if weight loss is less than 5% Regular weight measurements and BMI calculations Monitoring for adverse effects, particularly gastrointestinal symptoms Blood pressure and cardiovascular risk factor assessment Periodic blood tests to monitor metabolic parameters For patients with diabetes who are taking insulin or sulfonylureas, doses of these medications may need to be reduced when starting GLP-1 receptor agonists to prevent hypoglycaemia
Dark yellow or amber urine indicates you need to increase fluid intake immediately
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Failure to increase the number of secreted VLDL particles could indicate suboptimal apoB100 levels as a precipitating factor in NAFLD, and while mRNA levels of apoB100 and MTTP was found to be higher in patients with NAFLD compared to controls [35, 121], apoB100 synthesis rates were lower in patients with NASH ( n = 7) compared to lean ( n = 7) or BMI-matched obese ( n = 7) controls without NASH [122]
