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10.1371/journal.pone.0187504 PLoS One 33 JainM.GhanashyamC.BhattacharjeeA

But outside controlled studies, long-term treatment can be difficult to maintain because of cost, side effects, medication shortages, or limited insurance coverage

Depletion of mitochondrial glutathione has been associated with increased neuronal injury and has been implicated in the pathogenesis of several neurodegenerative diseases, including Alzheimers, Parkinsons, and multiple sclerosis