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However, the previous studies could not avoid the confounding effects of the endogenous carnitine background when attempting to evaluate the effects of administering exogenous l- or d-carnitine

For instance, according to a study conducted in 2022 by Nejati et al., taking L-carnitine orally led to a significant decrease in insulin, FBG, HOMA-IR, and insulin sensitivity ( Consequently, studies on the effect of L-carnitine supplementation and glycemic markers have shown different controversial findings based on studies and due to several factors, including dosage, duration, types of carnitines, and use of L-carnitine with other supplements intervention