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A pattern described by many users involves dramatic early improvement followed by a plateau

This treatment is aimed at reducing testosterone levels, improving symptoms such as hirsutism and acne, and restoring regular menstrual cycles (Teede et al., 2023)

Ximelagatran vs warfarin for stroke prevention in patients with nonvalvular atrial fibrillation: a randomized trial

Moreover IR in PCOS was shown to destroy the effect of gonadotropins, enhance the sensitivity of follicular membrane cells to the luteinizing hormone, and increase the expression of P450c17 and 3-hydroxysteroid dehydrogenase type 2, leading to increased production of androgen (152)